qpuowuvvm

Researchers report new species of deadly Ebola virus

first_img Nov 21 PLoS press releasehttp://www.eurekalert.org/pub_releases/2008-11/plos-sdn111908.php During the midst of the 2007 outbreak the World Health Organization announced Nov 30 that a new subtype of the virus was sickening people in Bundibugyo district. Researchers published a detailed account today on the discovery and an analysis of genetic findings of the new subtype in the Public Library of Science Pathogens (PLoS Pathogens). Nov 21, 2008 (CIDRAP News) – Researchers from the United States and Uganda today released the first full scientific report on a new Ebola species that struck western Uganda late last year and was linked to 149 suspected cases and 37 deaths, at least 4 of them healthcare providers. Unknown drug susceptibilityThe group concluded that researchers who are developing vaccines against the Zaire and Sudan Ebola viruses will probably want to do cross-protection studies to determine of the vaccines can be designed to protect against the Bundibugyo subtype. Using a less sensitive but more broadly reactive filovirus RT-PCR assay on one of the specimens, the scientists found more evidence of infection, which suggested the genetic sequence was distinct from the four known Ebola subtypes. In all, 9 of the 29 blood samples were positive for Ebola virus infection, the group reported. Before comparing the new subtype with other known filoviruses, the research team had to complete the entire genome of the new Ebola subtype as well as that of the Cote D’Ivoire Ebola virus. When comparing all of the species, they found that the newly discovered subtype—which they proposed naming the Bundibugyo Ebola virus—differed from the four existing types. Unusual symptoms point to new speciesDuring the 2007 outbreak, officials were puzzled because patients had unusual initial symptoms such as vomiting and others that resembled malaria, according to previous reports. Officials didn’t suspect Ebola right away, because some of the early case patients didn’t have external bleeding. See also: Using a new metagenomics pyrosequencing method developed by 454 Life Sciences, a Roche company based in Branford, Conn., the researchers were able to rapidly sequence 70% of the virus genome to develop a draft sequence that allowed them to quickly develop real-time PCR assays specific to the new virus subtype, according to the report. Towner JS, Sealy TK, Khristova ML, et al. Newly discovered Ebola virus associated with hemorrhagic fever outbreak in Uganda. PLoS Pathog 2008 Nov;4(11) (published online Nov 21)[Full text]center_img The investigators reported that the closest relative to the new species is the Cote d’Ivoire subtype, which shows a 32% nucleotide difference. The new assays were quickly sent to the Uganda Virus Research Institute to assist with diagnosis of Ebola patients during the rest of the outbreak. They said more studies are needed to determine the pathogenicity of the new virus and if antivirals are effective against it. According to initial findings from the outbreak, the case-fatality rate for Bundibugyo Ebola was about 36%, lower than that of the Zaire (80% to 90%) or Sudan (50% to 55%) subtypes. Dec 6, 2007, CIDRAP News story “Suspected cases rise as new Ebola strain strikes Uganda” Initial symptoms include fever, headache, joint and muscle aches, sore throat, and weakness, followed by diarrhea, vomiting, and stomach pain, according to the US Centers for Disease Control and Prevention (CDC). Some patients have both internal and external bleeding. There is no vaccine or specific treatment for the disease. In late November, health officials in Uganda sent 29 blood samples from suspect patients to the CDC. Using a broadly reactive Ebola virus antigen capture assay, the lab determined that eight specimens showed evidence of Ebola infection. However, earlier real-time reverse-transcription polymerase chain reaction (RT-PCR) assays for all known Zaire and Sudan Ebola viruses and Marburg viruses had shown that the specimens were negative. Four Ebola subtypes have previously been identified—Zaire, Sudan, Cote d’Ivoire, and Reston—but only the Zaire and Sudan subtypes have been associated with large hemorrhagic fever outbreaks in people in Africa. The Ebola virus is highly contagious and is lethal in about 50% to 90% of cases. Identification of the new virus highlights how quickly powerful molecular detection and characterization tools can identify new pathogens, the group wrote. However, they cautioned against solely relying on molecular techniques such as real-time PCR assays for detecting novel biodefense pathogens or conducting surveillance for emerging diseases.last_img read more

qpuowuvvm

Ferragosto and the Italian stampede are approaching our coast

first_imgItaly is one of the most important emitting markets for the Croatian tourism sector, from which we made more than a million arrivals last year alone.Ferragosto (from lat. Feriae Augusti = Feast of Augustus) is the name for the Feast of the Assumption, which is celebrated every August 15 in Italy, and is considered one of the most important religious and family holidays. At that time, many Italians go on vacation, and most take advantage of the entire vacation. It is already traditional, in return Ferragostu Croatia is the focus of most Italian media, which emphasize that our country has preserved its authenticity, ambience and traditional way of life and that it abounds in quality eno-gastronomy, but also a very attractive festival offer suitable for young Italian guests.So far this year, over 450 arrivals and more than 1.7 million overnight stays have been made from the Italian market, and the CNTB points out that the improving transport connections between Italy and Croatia are a stimulating factor for the growth of tourist traffic from this market.   The popularity of Croatia among Italians is proven by numerous publications in the most popular Italian mediaThe tourist magazine “Marco Polo” dedicated its cover to Primošten and Šibenik-Knin and Zadar counties, while “Caravan e Camper” published the cover and the text “Return to Dubrovnik” which describes the tourist offer of the city. “La stampa” points out that Croatia is not alone sun and sea and that in addition to the rich natural and cultural heritage, it offers popular music festivals, and he also wrote about his favorite Italian “Vogue” about Croatia and Vis. “Cosmopolitan “explored our beaches, or ten places where you can find paradise in Croatia. The famous tourist magazine “Bel Europa” published a special article about Croatia, and the cover is adorned with the island of Vis. The magazine, which has more than 450.000 readers, especially emphasized the importance of Croatian tradition and culture. The Croatian lighthouse Porer appeared on the cover of “DOVE”, as part of which a report on Lošinj, Brač, Hvar, Korčula and Mljet, as well as the lighthouses Porer and Veli Rat, was published.”Italian media are great fans and friends of Croatia and are very happy to write about our destinations and tourist offer. We are especially pleased with the significant growth in the interest of key Italian bloggers and influencers who have a large number of followers and who want to visit Croatia. This type of cooperation will be in an even stronger focus when planning activities for 2019. “, emphasized Viviana Vukelic, director of the CNTB Representation in Italy.   Also, the Italian state television company RAI 2 visited Croatia with the aim of exploring the Plitvice Lakes and Kornati National Parks. The show “Natural Beauties of Croatia” will be broadcast in the autumn program scheme with the aim of attracting Italian guests outside the peak of the tourist year. On the RETE 4 channel, the show “Parola di pollice verde” was broadcast, dedicated only to Croatia, the islands of Pašman, Pag and Lošinj, and Zadar and Split. Good cooperation with RETE 4 continues in September when the representatives of the show “Donna avventura” will visit Biograd na Moru and Trogir and discover new and still undiscovered Croatian destinations for their viewers. Istria and Kvarner are the most interesting for tourists from ItalyAccording to the shares in the total traffic so far, when it comes to the Italian market, Istria dominated with 47% of Italian overnight stays, followed by Kvarner with a share of 26% and Zadar County with a share of 6%.Favorite Italian destinations are Rovinj, Medulin, Porec, Mali Losinj, Novalja, Umag, Pula and Cres. Most Italians, 74% of our destination visited in an individual organization. Italians are above average prone to travel to Croatia during the peak of the tourist year, as many as 61% of arrivals and 73% of Italians’ overnight stays are recorded during July and August.CROATIAN WINNER OF THE “WORLD CHAMPIONSHIP” IN SKYSCANNER SEARCH TRAVELInterestingly, the Italian travel search engine Skyscanner.it in the week of the World Cup finals analyzed the search results for flights from Italy to the countries that played in the finals of this year’s championship, Croatia, France, Belgium and England. The goal of the statistics, which also took into account Russia, the host country of the World Cup, was to find out the “winner” in the selection of Italian passengers. The cities that had a large increase in search are Zagreb, Pula, Split, Zadar and Dubrovnik.With a total of five out of ten cities in the search table, Croatia is, in the opinion of users of the Italian portal Skyscanner, the “winner” of the World Cup. By the way, Skyscanner is the world’s leading search engine that offers a free search and comparison service for flights, hotels and car rentals. Founded in 2003, it is available in 30 languages, and every month, through it, more than 70 million people plan their trip.See more about the emitting market in the attachment.PROFILE: Issuing market profile – Italylast_img read more

qpuowuvvm

Bolt launches a new delivery service in 6 cities – Bolt Delivery

first_imgAs we know, every crisis is also an opportunity. Many companies were created at the time of the previous and thus the last financial crisis. This is how Bolt, the leading European platform for providing on-demand transport services, saw its opportunity and introduced a new service – Bolt Delivery. Using Bolt’s existing app, the delivery option offers the opportunity for private and business users to send what they need to their friends, family or business colleagues and associates during a period of limited mobility. The Bolt Delivery service is ideal for shipments that need to be delivered the same day, and even within just one hour such as clothes, books, household items, game consoles, documents and everything you need to send.  As of today, Bolt is launching a new service in Croatia, Bolt Delivery, ie a delivery service in Zagreb, Split, Rijeka, Osijek, Zadar and Dubrovnik.  “We will use, on the one hand, the existing technology and a large network of partner drivers throughout Croatia and enable users to be safe inside their home, at a time when the majority of the population is forced to do so. On the other hand, we launched the Bolt Delivery service in order to provide our partners with the best support, secure business and revenue opportunity with our experience and efficiency in business and logistics. In addition to this service, we plan to soon introduce new delivery services that will help business customers”Said Tomislav Lukačević, Operations Manager at Bolt, Croatia. Shipments should be lighter than 20 kg and within the specified dimensions up to a maximum of 65x55x40 cm, and for security, the service will be available only to those who have a valid bank card entered in their application because cash payment will not be possible. The minimum delivery price is 20 kuna for all cities. Photo: Bolt, Illustration: HrTurizam.hrlast_img read more

qpuowuvvm

Asian football body extends virus shutdown indefinitely

first_imgTopics : Football was one of the first sports affected by travel restrictions prompted by the coronavirus, which has now forced the blanket stoppage of professional sporting events worldwide. The Asian Football Confederation announced Tuesday the indefinite postponement because of the coronavirus of all matches scheduled for May and June, plunging the AFC Champions League into further disarray.The region’s premier club competition was put on hold in March as the pandemic spread, and the latest reshuffle means the 32-team group stage will have to be completed in July before the already-postponed knock-out rounds start a month later.”Following the continued preventive measures and travel restrictions put in place by several governments, the Asian Football Confederation has decided today to postpone all matches and competitions scheduled to take place in May and June until further notice,” an AFC statement said.center_img “As one of the first confederations in world football to undertake precautionary measures in light of the COVID-19 outbreak, the latest decision reinforces the AFC’s commitment to ensure the safety and wellbeing of players, participating teams, officials, fans and all stakeholders.”Less than two of the six rounds of group-stage matches have been completed so far, meaning the competition will face severe congestion even if it returns in July.The extended shutdown also affects the two-legged women’s Olympic qualifying play-off between China and South Korea, which had already been moved to June 1 and 9. June qualifiers for the men’s 2022 World Cup and 2023 Asian Cup had already been postponed.last_img read more

qpuowuvvm

Nearly one billion people scared of losing homes or land, poll finds

first_imgTopics : Almost one billion people around the world fear losing their homes or land within five years, with owners and tenants in Burkina Faso and the Philippines the most concerned, a survey of 140 nations showed on Wednesday.About one in five adults (19%) worry that their housing, fields or other land could be taken away from them in the near future, hampering their ability to invest or plan, according to the Prindex global property rights index.”Land and housing insecurity is a huge issue hiding in plain sight,” said Malcolm Childress, executive director of the Global Land Alliance, a Washington-based think tank that compiles the index with the British Overseas Development Institute. “It’s not surprising, given the unrest in both Burkina and the Philippines, that expressed levels of insecurity are rising,” said Karol Boudreaux, chief program officer at land rights charity Landesa.”Violent conflict displaces many people, and those left as well as powerful actors take advantage to seize properties,” she said in emailed comments.The survey, conducted by US polling firm Gallup and launched on Wednesday, is the largest-ever effort documenting how secure people feel about their homes and land at a global level.Although data collection was completed before the global outbreak of the novel coronavirus, housing insecurity could further increase as the easing of lockdowns in cities may lead to a rise in evictions, Childress said.”We already have a lot of insecurity globally and the pandemic has thrown a huge shock on top of that,” he said. “The United States for example is facing a massive eviction crisis.”Improving land and housing security will require training and awareness campaigns for people to exercise their rights and prove property ownership, and protecting renters from evictions, the report said.For example, authorities from Colombia to Nepal are using digital evidence such as photographs to establish property claims, in particular for the estimated 70 million people who have been forced from their homes by wars, natural disasters and other events.Nearly 170,000 people in 140 countries were questioned about ownership or tenure for the index.Prindex is an initiative of PlaceFund – a venture fund with which the Thomson Reuters Foundation has a partnership on property rights coverage – and the UK’s Department for International Development. center_img “Tenure security is important for individual decision making and has knock-on effects on what people do with their assets, whether they send their kids to school, or invest in better crops,” he told the Thomson Reuters Foundation.A lack of formal documentation and poor implementation of land laws threaten tenure in many countries, experts say, with more than 5 billion people lacking proof of ownership, according to the Lima-based Institute for Liberty and Democracy.People in the Philippines and Burkina Faso reported the highest levels of concern, with nearly half of respondents (48% and 44%) fearing their homes could be taken away.That compared with Singapore and Rwanda, which had the lowest rates of concern in the same two regions, with 4% and 8% respectively.last_img read more

qpuowuvvm

‘Test-&-trace’ crucial but won’t beat coronavirus alone: Study

first_imgAnything above “1” means the disease is continuing to expand; below that threshold, it will eventually peter out.Some countries that brought the spread of COVID-19 under control but are now struggling to prevent a resurgence have R numbers well above 1. In France, for example, it hovered at about 1.33 during the first week of August, according to national health authorities.But the new finding comes with a caveat, said lead author Nicholas Grassly, a professor at Imperial College’s School of Public Health. Herd immunity not close In the United States and the UK, delays can be even longer.Even if nations do adhere to these guidelines, it will still not be enough to bring the infection rate down sufficiently by itself, the new study concludes.”Test and trace alone won’t be enough to control transmission in most communities, and other measures alongside will be needed to bring the R number below 1,” said Grassly.Weekly screening of high-risk groups such as health and social-care workers — regardless of whether they have symptoms or not — can reduce transmission by an additional 23 percent, his team found.Experts are still unsure as to what percentage of a population must be immune — a threshold known as “herd immunity” — to prevent the virus from continuing to spread. Estimates range from below 50 to 70 percent.It is possible that some of the hardest hit regions — New York City, northern Italy — may be close to these levels, but at a national scale the numbers are still far lower, probably barely in double digits.WHO emergencies director Michael Ryan said Tuesday that the planet was “nowhere close to the levels of immunity required to stop this disease”.People should “not live in hope of herd immunity being our salvation. Right now, that is not a solution,” he added.A vaccine, of course, would also provide immunity, but is unlikely to be available until next year.Currently, only people who have fought off COVID-19 and survived have some degree of immunity, though it remains unclear how robust it is and how long it lasts.It is also unclear the extent to which people with mild or asymptomatic cases have immunity at all. The novel coronavirus has killed nearly 775,000 people and infected almost 22 million since the outbreak emerged in China last December, according to a tally from official sources compiled by AFP.   Testing for COVID-19 and tracing the prior contacts of those found to be infected are crucial measures for slowing the disease’s spread, but inadequate unless combined with other measures, researchers said Wednesday.By itself, the test-and-trace approach can reduce the virus’ reproduction rate, or R number, by 26 percent, they reported in The Lancet Infectious Diseases, using mathematical models to examine data from previously published studies.The reproduction rate measures the number of people in a population, on average, infected by each person carrying the virus. “Our results show that test and trace can help reduce the R number but needs to be carried out effectively and quickly to do so,” he said in a statement. Concretely, that means immediate testing with the onset of symptoms and results within 24 hours; the quarantine of contacts, also within 24 hours; and the identification of 80 percent of cases and contacts.Very few countries — notably South Korea, Taiwan and Germany — have come close to staying within these guidelines, and most are still falling well short.In France, for example, it generally take days to get an appointment for a so-called PCR nasal test, and on average 3.5 days for a result, according to official figures. Topics :last_img read more

qpuowuvvm

“Sex Change” Surgery: What Bruce Jenner and You Should Know

first_imgPublic Discourse 27 April 2015Bruce Jenner and Diane Sawyer could benefit from a history lesson. I know, because I suffered through “sex change” surgery and lived as a woman for eight years. The surgery fixed nothing—it only masked and exacerbated deeper psychological problems.The beginnings of the transgender movement have gotten lost today in the push for transgender rights, acceptance, and tolerance. If more people were aware of the dark and troubled history of sex-reassignment surgery, perhaps we wouldn’t be so quick to push people toward it.The setting for the first transgender surgeries (mostly male-to-female) was in university-based clinics, starting in the 1950s and progressing through the 1960s and the 1970s. When the researchers tallied the results and found no objective proof that it was successful—and, in fact, evidence that it was harmful—the universities stopped offering sex-reassignment surgery.Since then, private surgeons have stepped in to take their place. Without any scrutiny or accountability for their results, their practices have grown, leaving shame, regret, and suicide in their wake.http://www.thepublicdiscourse.com/2015/04/14905/?utm_source=The+Witherspoon+Institute&utm_campaign=a01e2a3404-RSS_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_15ce6af37b-a01e2a3404-84094405last_img read more

qpuowuvvm

P40,000 bail bond for drug suspect

first_imgPolice officers served the warrantissued by Judge Walter Zorilla of the Regional Trial Court Branch 55 inHimamaylan City dated March 13, 2020. Nabaja was detained in the HimamaylanCity police station’s lockup facility./PN BACOLOD City – The court recommended aP40,000 bail bond for the temporary liberty of a man facing illegal drugcharges in Barangay Mahalang, Himamaylan City, Negros Occidental. Resident Rodrigo Nabaja, 41, was caught on the strength of an arrest warrantaround 10:20 a.m. on April 23, police said.last_img

qpuowuvvm

Switzerland County native, state trooper graduates from FBI Academy

first_imgQuantico, Va. — Switzerland County native and Indiana State Police Lt. Delmer Gross recently graduated from the FBI National Academy Program in Quantico, Virginia. The class of 224 included men and women from 48 states, 22 countries and five different military organizations.The program is an internationally recognized 10-week training program for advanced communications, leadership and fitness training. Class participants have proven records within their agencies and on average have about 20 years of law enforcement experience. Instruction is conducted by the FBI Academy and special agents.Appointed to the Indiana State Police in 1989, Delmer began his career at the Sellersburg Post and worked road patrol duties until his promotion to district detective in 1995. In 2004 he was promoted to Sergeant in the Laboratory Division as a polygraph examiner where he worked until his current promotion to Lieutenant as the Area IV Investigative Commander.Other officers attending from Indiana included Capt. Matthew A. Feller, Peru PD; Lt. Michael K. Horn, Marian University; and Lt. Michael P. Taylor, Fishers PD.last_img read more

qpuowuvvm

Forecasters: Temperatures moderate, storms possible

first_imgWilmington, Oh. — Forecasters say temperatures may moderate slightly into the mid-80s for Wednesday and showers or thunderstorms are likely after 3 p.m. The storms could produce high winds and locally heavy rain that could result in flooding.last_img